Typical Demethylation Events in Cloned Pig Embryos
نویسندگان
چکیده
منابع مشابه
Ascorbic acid increases demethylation in somatic cell nuclear transfer embryos of the pig (Sus scrofa)
OBJECTIVE Investigated the effect and mechanism of ascorbic acid on the development of porcine embryos produced by somatic cell nuclear transfer (SCNT). METHODS Porcine embryos were produced by SCNT and cultured in the presence or absence of ascorbic acid. Ten-eleven translocation 3 (TET3) in oocytes was knocked down by siRNA injection. After ascorbic acid treatment, reprogramming genes were ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.m106516200